Number of COVID-19 cases required in a population to detect SARS-CoV-2 RNA in wastewater in the province of Alberta, Canada: Sensitivity assessmentResearch article Published on 2023-03-012022-10-05 Journal: Journal of environmental sciences (China) [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] analysis Analysis collected Community COVID-19 COVID-19 case COVID-19 cases Critical dataset defined detect detection rate Detection sensitivity Epidemiology Estimated IMPROVE input median negative test number plant positive prevalence of COVID-19 Probability Probit analysis provided required RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection sensitivity study period Support Surveillance threshold Treatment unique wastewater [DOI] 10.1016/j.jes.2022.04.047 [Article Type] Research article
Application of neighborhood-scale wastewater-based epidemiology in low COVID-19 incidence situationsArticle Published on 2022-12-152022-11-16 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, [키워드] application applied approach average characterized Concentration COVID-19 COVID-19 incidence Disease surveillance effective Epidemiology incidence rate infections less limit local outbreak Low COVID-19 incidence Mild N gene Neighborhood-scale sewersheds normalized outbreak plant public health measure quantification reported RT-qPCR SARS-CoV-2 SARS-CoV-2 N gene SARS-CoV-2 variant-specific RT-qPCR assays sensitivity Seven specificity statistically Surveillance the SARS-CoV-2 threshold Treatment virus Wastewater-based epidemiology. [DOI] 10.1016/j.scitotenv.2022.158448 PMC 바로가기
Humoral response and safety of the third booster dose of BNT162b2 mRNA COVID-19 vaccine in patients with multiple sclerosis treated with ocrelizumab or fingolimodArticle Published on 2022-12-012022-11-15 Journal: Journal of Neurology [Category] COVID19(2023년), SARS, 진단, [키워드] binding antibody unit BNT162b2 mRNA BNT162b2 mRNA vaccine booster dose collected Control COVID-19 COVID-19 vaccine dose expressed fingolimod HCs humoral Humoral response IgG IgG antibody IgG level Laboratory mRNA mRNA vaccine Multiple multiple sclerosis Ocrelizumab Ocrelizumab. of BNT162b2 Patient positive predict quantified reported SARS-CoV-2 sclerosis serum sample severe adverse event socio-demographic threshold Tolerability treated Trimeric spike protein Vaccine vaccine dose variable [DOI] 10.1007/s00415-022-11296-4 PMC 바로가기
RT-LAMP assay for rapid detection of the R203M mutation in SARS-CoV-2 Delta variantSARS-CoV-2 Delta 변이체에서 R203M 돌연변이의 신속한 검출을 위한 RT-LAMP 분석Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Accuracy amplification analyses appear AUC clinical samples conserved COVID-19 COVID-19 vaccines Delta delta variant Delta variants detect determined by Diagnosis discrepancy dominant Efficiency facilitate genotyping infected individuals Mutation N gene positive sample Primers quantification quarantine R203M mutation Rapid rapid diagnosis. RT-LAMP RT-qPCR SARS-CoV-2 sensitivity sequence Sequencing sets of primer sets of primers specificity specimen Surveillance threshold variant variants [DOI] 10.1080/22221751.2022.2054368 PMC 바로가기 [Article Type] Article
Evaluation of commercially available fully automated and ELISA-based assays for detecting anti-SARS-CoV-2 neutralizing antibodiesArticle Published on 2022-11-082022-11-15 Journal: Scientific Reports [Category] SARS, 치료기술, [키워드] acute respiratory syndrome administration affecting Analysis analysis anti-RBD IgG antibody anti-SARS-CoV-2 AUC automated binding antibody booster clinical settings Cohort collected Control coronavirus correlation COVID-19 cutoff value demonstrated Effectiveness Genscript gold standard Immunity immunoassay in both groups infected patient Mindray NAb neutralization Neutralization assay neutralization test neutralizing antibody population level protective immunity provide pseudovirus R 2 Rapid receiver operating characteristic Research ROC ROC Curve Sample SARS-CoV-2 SARS-CoV-2 infected patient second dose sensitivity shown significantly specificity subjects sVNT sVNT assay symptoms onset tested threshold vaccinated individual Vaccine virus neutralization test was performed [DOI] 10.1038/s41598-022-21317-x PMC 바로가기
Mathematical modeling to study the impact of immigration on the dynamics of the COVID-19 pandemic: A case study for VenezuelaResearch article Published on 2022-11-012022-10-05 Journal: Spatial and spatio-temporal epidemiology [Category] SARS, 변종, [키워드] Affect affected Asymptomatic carriers basic reproduction number COVID-19 COVID-19 pandemic decrease Epidemiology Evolution FIVE identify Immigration Intervention less mathematical mathematical modeling Mild number of infected outcome pandemic parameter Perspective predict public health SARS-CoV-2 SARS-CoV-2 virus Spread susceptible the disease the SARS-CoV-2 threshold transmission rate Venezuela [DOI] 10.1016/j.sste.2022.100532 [Article Type] Research article
Evaluation of Procalcitonin’s Utility to Predict Concomitant Bacterial Pneumonia in Critically Ill COVID-19 PatientsArticle Published on 2022-11-012022-11-15 Journal: Journal of Intensive Care Medicine [Category] 바이오마커, [키워드] Antibiotic therapy AUC Bacteremia Bacterial Bacterial infection bacterial pneumonia baseline characteristics Concomitant conducted COVID-19 creatinine Critical Critical illness Critically ill patient Culture defined determine diagnosing diagnostic ENhance evaluate group hospitalized patients ICU ICU patient identify Ill in-hospital mortality intensive care intensive care unit Mortality multivariable multivariable model no difference no significant difference offer outcome Patient PCT Pneumonia positive predict Predictive procalcitonin procalcitonin. receiver operating characteristics Regression model retrospective cohort study ROC SARS-CoV-2 secondary bacterial pneumonia serum creatinine Severe COVID-19 pneumonia Severity of disease specificity threshold utility variable vital signs was used while with COVID-19 [DOI] 10.1177/08850666221108636 PMC 바로가기
Pandemic driven innovation: A pilot evaluation of an alternative respiratory pathogen collection deviceArticle Published on 2022-11-012022-11-16 Journal: The American journal of emergency medicine [Category] SARS, 유전자 메커니즘, [키워드] absence All participant amplification communicable disease COVID-19 demonstrated determine diagnostic enrolled evaluated faster favor feedback fused gold standard identify inhibitor Innovation Interpretation invasive mechanism nasopharyngeal Nasopharyngeal swab nucleic acids participant Patient PCR PCR cycle PCR testing pilot study polymerase chain positive producing real-time reverse transcriptase receiving respiratory respiratory pathogen respiratory virus Result resulting RNase P RNAseP RT-qPCR Self-collection respiratory pathogen device. specimen study participant TaqPath tested threshold [DOI] 10.1016/j.ajem.2022.08.047 PMC 바로가기
Sensor-based surveillance for digitising real-time COVID-19 tracking in the USA (DETECT): a multivariable, population-based, modelling studyArticle Published on 2022-11-012022-11-15 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] Advancing aggregation Apple average baseline behavioural calculated Care CDC center change Cohort collected Combination Control correlation COVID-19 COVID-19 case diagnostic disease enrolled example fill out Google Fit individual information laboratory data multivariable participant participated Pearson correlation Pearson correlation coefficient physiological prevention proportion real time recruited reported Rockefeller Foundation Science seeking sensor significantly study period Surveillance symptom onset Symptoms threshold Traditional transfer USA validation cohort was used Web [DOI] 10.1016/S2589-7500(22)00156-X PMC 바로가기
Severe Acute Respiratory Syndrome Coronavirus 2 Delta Vaccine Breakthrough Transmissibility in Alachua County, FloridaArticle Published on 2022-10-292022-11-16 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), SARS, 변종, [키워드] acute infection acute respiratory syndrome association average booster caused Characteristics conducted Contact Contact tracing coronavirus coronavirus 2 Delta delta variant Epidemic evaluate exhibited Florida genomes Immunity Infection interquartile range Lineage majority occurred Patient Phylogenetic Phylogenetic analysis public health question raising regression analysis respiratory SARS-CoV-2 SARS-CoV2 sequence sequenced Spread threshold through contact Transmissibility Transmission vaccinated individual vaccinated individuals vaccination vaccination. Vaccine vaccine dose Viral RNA viral RNA quantification were used [DOI] 10.1093/cid/ciac197 PMC 바로가기